Unveiling the potential of Hamigeran-B from marine sponges as a probable inhibitor of Nipah virus RDRP through molecular modelling and dynamics simulation studies.

The Nipah virus (NiV) is an emerging pathogenic paramyxovirus that causes severe viral infection with a high mortality rate. This study aimed to model the effectual binding of marine sponge-derived natural compounds (MSdNCs) towards RNA-directed RNA polymerase (RdRp) of NiV. Based on the functional relevance, RdRp of NiV was selected as the prospective molecular target and 3D-structure, not available in its native form, was modelled.

Enhanced Drive Current in 10 nm Channel Length Gate-All-Around Field-Effect Transistor Using Ultrathin Strained Si/SiGe Channel.

The continuous scaling down of MOSFETs is one of the present trends in semiconductor devices to increase device performance. Nevertheless, with scaling down beyond 22 nm technology, the performance of even the newer nanodevices with multi-gate architecture declines with an increase in short channel effects (SCEs). Consequently, to facilitate further increases in the drain current, the use of strained silicon technology provides a better solution.

Sustainable oxalic acid treatment of lignocellulosic fibers for ensuring improved performance of treated fibers based bio PBS composites.

Plant-based macromolecules such as lignocellulosic fibers are one of the promising bio-resources to be utilized as reinforcement for developing sustainable composites. However, due to their hydrophilic nature and weak interfacial bonding with polymer matrices, these fibers are mostly incompatible with biopolymers. The current research endeavor explores the novel eco-friendly oxalic acid (CHO.

A phase I study of convection-enhanced delivery (CED) of liposomal-irinotecan using real-time magnetic resonance imaging in patients with recurrent high-grade glioma.

Background: Irinotecan demonstrates anti-tumor efficacy in preclinical glioma models but clinical results are modest due to drug delivery limitations. Convection enhanced delivery (CED) improves drug delivery by increasing intratumoral drug concentration. Real-time magnetic resonance imaging of infusate delivery during CED may optimize tumor coverage.

Navigating trends in research related to vestibular function tests through scientometrics.

Purpose: Research on vestibular function tests has advanced significantly over the past century. This study aims to evaluate research productivity, identify top contributors, and assess global collaboration to provide a comprehensive overview of trends and advancements in the field.

Method: A scientometric analysis was conducted using publications from the Scopus database, retrieved on January 5, 2024.