VIA (Visual Inspection with Acetic Acid) is commonly used for cervical cancer screening in low-resource areas due to its simplicity, but a study in Andhra Pradesh, India, found its sensitivity for detecting significant cervical lesions (CIN2+) to be only 26.3%, much lower than established benchmarks of 60-90%.
In the study, only 5 out of 19 women with CIN2+ tested positive via VIA, indicating a very low positive predictive value of 3.1%.
Factors influencing VIA positivity included older age, positive Pap tests, visible cervical inflammation, and variability among different examiners, highlighting that VIA's subjective nature limits its reliability as a primary screening tool in these settings.