Publications by authors named "K Van Herle"

Background/purpose: Intra hospital transfer of sick newborns is known to cause adverse events with potential morbidity. Interventions at the bedside in a sick neonate can reduce the need for transport and in turn, potential hazards of transfer. Our single institute experience of performing bedside laparotomies in unstable newborns is reported here.

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Background: Double J (DJ) stents placed at the end of paediatric urological procedures require another cystoscopy under general anaesthesia for removal. The second author developed a reproducible technique for snaring the DJ stent using an infant feeding tube (6-Fr or 8-Fr) and a 3-0 polypropylene suture per urethra. Having demonstrated the proof of concept, ethical clearance was obtained for an institutional randomised controlled trial.

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Article Synopsis
  • Pediatric urethral strictures in boys were studied to understand their causes and treatment outcomes over an 11-year period, excluding cases related to hypospadias repair.
  • The most prevalent cause was trauma, particularly pelvic injury, with a notable 82% overall success rate for surgical interventions, although nearly half of the patients required redo surgeries.
  • The study concluded that surgeries aimed to connect healthy urethra sections are often necessary due to the nature of the strictures, and the surgical approach depends on the stricture's location and severity.
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Article Synopsis
  • Wireless capsule endoscopy (WCE) is a major advancement in gastroenterology that allows for painless imaging of hard-to-reach areas in the small intestine.
  • The most frequent complication associated with WCE is the retention of the capsule within the body.
  • In a reported case, a child undergoing evaluation for obscure gastrointestinal bleeding experienced capsule retention, necessitating surgical intervention after two weeks of conservative monitoring.
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Neuromyelitis optica (NMO) (and NMO spectrum disorder) is an autoimmune inflammatory disease of the CNS primarily affecting spinal cord and optic nerves. Reliable and sensitive biomarkers for onset, relapse, and progression in NMO are urgently needed because of the heterogeneous clinical presentation, severity of neurologic disability following relapses, and variability of therapeutic response. Detecting aquaporin-4 (AQP4) antibodies (AQP4-IgG or NMO-IgG) in serum supports the diagnosis of seropositive NMO.

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