Determination of Bile Acids in Canine Biological Samples: Diagnostic Significance.

The comprehensive examination of bile acids is of paramount importance across various fields of health sciences, influencing physiology, microbiology, internal medicine, and pharmacology. While enzymatic reaction-based photometric methods remain fundamental for total BA measurements, there is a burgeoning demand for more sophisticated techniques such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) for comprehensive BA profiling. This evolution reflects a need for nuanced diagnostic assessments in clinical practice.

Agenesis of pancreas and gall-bladder in an infant of incest.

Fatal diabetic coma was observed in a small-for-gestational-age newborn of brother-sister incest. Post mortem examinations revealed congenital absence of the pancreas and gall-bladder.