[A comparison analysis of the use of intravenous β-interferon-1a 30 mcg and subcutaneous β-interferon-1a 44 mcg in routine clinical practice of treatment in patients with multiple sclerosis].

Objective: to compare the results of treatment of multiple sclerosis (MS) with genfaxon, cinnovex and rebif.

Material And Methods: The drugs were used in the treatment of 80 patients of the Moscow West administrative okrug during 2014-2015. Thirty patients were treated with genfaxon, 20 with cinnoVex and 30 with the original drug rebif.

[Preventive and cessation therapy of mental disorders in patients with the acute coronary syndrome].

An open prospective trial of 93 inpatients divided into two main groups (61 patients) - with mental disorders (31) and without mental disorders (30) and a comparison group (32 patients) was carried out. All patients survived the acute coronary syndrome (myocardial infarction, unstable angina). The efficacy and safety of both preventive and cessation therapy with pantogam active in mean doses 1.

[The clinical significance of renal functional reserve].

Patients at risk to develop intraglomerular hypertension were denoted among those with chronic glomerulonephritis (CGN) basing on the relationships between various clinico-laboratory findings, clinical syndromes and markers of intraglomerular hypertension (low or absent renal functional reserve). The risk groups include CGN patients with urinary syndrome and arterial hypertension with nephrotic disease and serum creatinine over 1.4 mg/%, with renal damage typical for focal-segmental glomerulosclerosis or fibroplastic glomerulonephritis.

[Disorders of intrarenal hemodynamics in glomerulopathies].

The intrarenal hemodynamics was examined in 101 patients with chronic glomerulonephritis (CGN) and 111 patients with type I diabetes mellitus. Intrarenal hypertension was diagnosed from renal functional reserve (RFR) depletion. In CGN intrarenal hypertension was revealed in all clinical and morphological variants of nephritis: in 40% of patients with a nephrotic variant, in 25% with a latent variant and in 83% of patients with nephritis concurrent with the severe urinary syndrome.

[The antiproteinuric action of angiotensin-converting enzyme inhibitors in chronic glomerulonephritis and diabetic nephropathy].

Antiproteinuria effects of angiotensin-converting enzyme (ACE) inhibitors was studied in 23 patients with chronic nephritis (CN) and 32 patients with diabetic nephropathy (DN). CN patients received Capoten, DN patients were given enalapril. The drugs were also examined for the action on systemic arterial pressure, renal function and intrarenal hemodynamics.