Long-term outcomes of women compared to men after off-pump coronary artery bypass grafting-a propensity-matched analysis.

Background: Literature is not clear whether women experience increased mortality and adverse events after coronary artery bypass grafting (CABG). Studies have shown that women had comparative outcomes to men in off-pump CABG (OPCAB). Hence, we undertook this study to understand the short- and long-term outcomes of women compared to men after OPCAB.

Design, Safety and Efficacy Evaluation of Gemcitabine-eluting Nanoyarn-integrated Heparinized Self Expanding Metallic Stents for Long-Term Management of Malignant Biliary Obstruction.

Malignant biliary obstruction presents a significant therapeutic challenge and has serious consequences including cholangitis and death. Clinically, biliary stenting using self-expanding metallic- stent(SEMS) relieves this obstruction. However, stent occlusion occurs with time due to tumor/epithelial in-growth and bacterial colonization.

A Pilot Dashboard System to Track Cumulative Exposure to Sound Levels during Music Instruction: A Technical Report.

Background:  Music-induced hearing loss (MIHL) is a critical public health issue. During music instruction, students and teachers are at risk of developing hearing loss due to exposure to loud and unsafe sound levels that can exceed 100 dBA. Prevention of MIHL in music students must be a desired action of all music educators.

Emerging AXL Inhibitors in Oncology: Chemical and Biological Advances in Targeted Cancer Therapy.

AXL, a receptor tyrosine kinase, has emerged as a critical player in tumorigenesis, metastasis, and resistance to conventional therapies. Its aberrant activation drives cell proliferation, survival, and angiogenesis, making it an attractive target for cancer treatment. In recent years, significant progress has been made in the development of AXL inhibitors.

HIV-1 single transcription start site mutants display complementary replication functions that are restored by reversion.

HIV-1 transcription initiates at two positions, generating RNAs with either 1G or 3G 5' ends. The replication fates of these RNAs di\er, with viral particles encapsidating almost exclusively 1G RNAs and 3G RNAs retained in cells where they are enriched on polysomes and among spliced viral RNAs. Here, we studied replication properties of virus promoter mutants that produced only one RNA 5' isoform or the other: separately, in combination, and during spreading infection.