[Comparative study on the effect of antiatherosclerotic diet enriched with polyunsaturated omega-3 fatty acids of plant and animal origin on the level of natural antibodies against catecholamines in patients with cardiovascular diseases].

The levels of natural antibodies against catecholamines in 138 patients with cardiovascular diseases was studied and the comparative analysis of influence of antiatherosclerotic diets with different origin of PUFA omega-3 on dynamic of these parameters was made. For the first time discovered universal action of diets with PUFA omega-3 vegetable and animal origin on parameters of humoral immunity: in case of primary excess of norm of the contents of natural antibodies to adrenaline, noradrenaline and dopamine as a result of treatment these parameters were reduced or did not change; and at is primary a low their level--parameters increased in most cases. The greatest immunocorrection effect was rendered by diet, enriched PUFA omega-3 of freshwater fishes fat.

[Study of metabolic and clinical effects of polyunsaturated fatty acids omega-3 from "Eicovit" in patients with ischemic heart disease and familial hyperlipoproteinemia].

The influence of antiatherosclerotic diet with including 15 g preparation "Eikovit" containing fat of freshwater fish on fat acid composition of erythrocytes membrane was studied in 399 patients with ishemic heart disease and hyperlipidemia. Against a background of positive influence on clinical symptoms of diseases, lipids of blood serum, homeostasis expressed influence of PUFA omega-3 in "Eikovit" on biomembrane fat acid composition was noted. It was shown sharp increasing a quota an eicosapentaenic acid by simultaneous reducing PUFA omega-6 level.

[Effect of diet including omega-3 polyunsaturated fatty acids on the status of T-cell immunity in patients with ischemic heart disease and hyperproteinemia].

Use of antisclerotic diet in patients with ischemic heart disease and hyperlipidemia promoted positive changes of clinical symptoms of diseases, some parameters of lipid metabolism and T-cellular immunity. Including in diet polyunsaturated fatty acids promoted increasing of its hypolipidemic effect.

[Lipid peroxidation in patients with ischemic heart disease, hyperlipidemia and/or hypertension while polyunsaturated omega-3 fatty acids of plant and animal origin were in their diet].

Usage of antisclerotic diet with PUFA n-3 from vegetable or animal source in 326 patients with IHD, HL and HBP resulted in positive dynamic of clinical manifestation, blood lipids and coagulogramms of the patients. The favorable changes of membrane lipids and the decrease of intensity of lipid peroxidation was also revealed. The decrease of primary and secondary metabolites of lipid peroxidation could be a result of hypolipidemic effect of the diets and sufficient level of vitamin E.