Publications by authors named "K V Somasundaram"
To determine behind armor blunt trauma (BABT) injury criteria, experiments have been conducted by launching blunt projectiles at live swine at velocities up to 65 meters per second (m/s) using one type of indenter design. To ensure the generalizability of the developed injury criteria, additional tests with different indenter designs are needed. The objectives of this study were to evaluate the kinematics and injury parameters from two indenter designs using human body finite element modeling.
View Article and Find Full Text PDFBackground: Future Health Today (FHT) is a technology program that integrates with general practice clinical software to provide point of care (PoC) clinical decision support and a quality improvement dashboard. This qualitative study looks at the use of FHT in the context of cardiovascular disease risk in chronic kidney disease (CKD).
Objective: This study aims to explore factors influencing clinical implementation of the FHT module focusing on cardiovascular risk in CKD, from the perspectives of participating general practitioner staff.
Article Synopsis
- Researchers found a long noncoding RNA called RIM28 that inhibits the tumor suppressor p53 in glioblastoma (GBM) and glioma stem-like cells (GSC), leading to worse cancer outcomes.
- This RNA interacts with a specific mRNA that increases TRIM28 protein, which in turn decreases p53 levels through enhanced ubiquitination, reducing the effectiveness of p53's DNA damage response.
- Silencing RIM28 suppressed GSC growth and reduced glioma tumors, while its overexpression promoted tumor growth and resistance to the chemotherapy drug Temozolomide, suggesting it could be a potential therapeutic target for GBM treatments.
Ego4D: Around the World in 3,000 Hours of Egocentric Video.
IEEE Trans Pattern Anal Mach Intell
July 2024
We introduce Ego4D, a massive-scale egocentric video dataset and benchmark suite. It offers 3,670 hours of daily-life activity video spanning hundreds of scenarios (household, outdoor, workplace, leisure, etc.) captured by 931 unique camera wearers from 74 worldwide locations and 9 different countries.
View Article and Find Full Text PDFObjective: Multiple studies evaluate relative risk of female vs. male crash injury; clinical data may offer a more direct injury-specific evaluation of sex disparity in vehicle safety. This study sought to evaluate trauma injury patterns in a large trauma database to identify sex-related differences in crash injury victims.
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