Publications by authors named "K V Shivaprasad"
Developing early maturing lentil has the potential to minimize yield losses, mainly during terminal drought. Whole-genome resequencing (WGRS) based QTL-seq identified the loci governing earliness in lentil. The genetic analysis for maturity duration provided a good fit to 3:1 segregation (F), indicating earliness as a recessive trait.
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- The study identifies a large number of insertion/deletion (InDel) polymorphisms in the lentil genome, which can help in mapping traits related to growth duration, specifically earliness in flowering.
- Through whole-genome resequencing of two extreme bulks (early and late flowering) and a parental genotype, researchers discovered 734,716 novel InDels, with a significant amount providing potential for marker-assisted selection (MAS).
- The identified InDel markers, especially I-SP-356.6, show promise for facilitating the transfer of early maturity traits to other lentil varieties, highlighting their value in developing faster-growing cultivars.
Article Synopsis
- Yellow mosaic disease (YMD) poses a significant challenge to mungbean production, and research on short-duration genotypes helps mitigate heat stress during summer crops.
- A genome-wide association study (GWAS) involving 132 mungbean genotypes identified 31,953 single nucleotide polymorphisms (SNPs) across the genome, uncovering genetic diversity and significant traits related to flowering time and disease resistance.
- Candidate genes linked to various traits were identified, including those for YMD resistance and flowering time, providing insights for future marker-assisted breeding efforts to develop improved mungbean varieties.
Article Synopsis
- Subramanian Kannan’s study focuses on monitoring serum thyroglobulin (Tg) and thyroglobulin antibody (TgAb) levels in patients with differentiated thyroid cancer (DTC) who underwent thyroid lobectomy or hemithyroidectomy in India, highlighting a gap in existing data.
- Of the 247 DTC patients reviewed from 2015 to 2020, 17 had lower tumor sizes and varied post-surgery Tg levels, with a median follow-up time of 15 months.
- The results showed mixed trends in Tg levels post-surgery; while most patients had Tg levels below 30 ng/mL, only 23% met the criteria for an "excellent response," suggesting challenges
Background And Aims: No meta-analysis has analysed efficacy and safety of semaglutide in metabolic-dysfunction associated fatty-liver disease (MAFLD).
Methods: Electronic databases were searched for RCTs involving people with MAFLD and/or type-2 diabetes (T2DM) receiving semaglutide. Primary outcome was to evaluate changes in alanine aminotransferase (ALT).