Publications by authors named "K V Kishore"
Endocrine therapies targeting the estrogen receptor (ER/ESR1) are the cornerstone to treat ER-positive breast cancers patients, but resistance often limits their effectiveness. Notable progress has been made although the fragmented way data is reported has reduced their potential impact. Here, we introduce EstroGene2.
View Article and Find Full Text PDFElectrochemical alkaline water electrolysis offers significant economic advantages; however, these benefits are hindered by the high kinetic energy barrier of the water dissociation step and the sluggish kinetics of the hydrogen evolution reaction (HER) in alkaline media. Herein, the ensemble effect of binary types of Rh single atoms (Rh-N and Rh-O) on TiO-embedded carbon nanofiber (Rh-TiO/CNF) is reported, which serves as potent active sites for high-performance HER in anion exchange membrane water electrolyzer (AEMWE). Density functional theory (DFT) analyses support the experimental observations, highlighting the critical role of binary types of Rh single atoms facilitated by the TiO sites.
View Article and Find Full Text PDFArticle Synopsis
- Transplant Renal Artery Stenosis (TRAS) is the most common vascular issue after kidney transplants, linked to higher rates of transplant failure and mortality.
- A study at a major transplant center focused on identifying risk factors for clinical TRAS (cTRAS) in living donor kidney transplants, revealing that arterial vascular reconstruction of multiple renal arteries (VR-MRA) significantly raises the risk of cTRAS.
- Among diagnosed cTRAS cases, a majority received successful endovascular treatment, leading to outcomes in graft and patient survival comparable to those without cTRAS, emphasizing the importance of early screening and prompt intervention.
Article Synopsis
- This study investigates the patterns of amphetamine-type stimulant (ATS) use and high-risk behaviors among adults in Manipur, India, revealing that the majority of users engage in daily use and dependence on substances.
- Most participants reported significant health issues related to ATS, including a tendency to inject drugs and risky sexual behavior, such as unprotected sex.
- The findings indicate a need for targeted strategies in India to address and reduce ATS use and its associated physical and psychological consequences.
Background: There are guidelines recommending the use of Indwelling pleural catheter (IPC), but there is no established consensus or guidelines regarding the modality of drainage post-IPC insertion. We have devised a novel drainage technique that combines the advantages of both aggressive and symptom-guided drainage.
Method: This was a prospective intervention trial in which patients with malignant pleural effusion, drained with IPC, were initially given one week of 'high-intensity' drainage on an outpatient basis using a low-pressure suction pump, followed by symptom-based home drainage using vacuum bottles.