Publications by authors named "K Unnikrishnan"

Downer cow syndrome, or secondary recumbency, is a condition primarily affecting dairy cows, where the animal is unable to rise and stand, due to unknown cause. It is usually associated with poor prognosis. Terminal downers are euthanized in most countries.

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Objectives: To compare the incidence of delirium and early (at 1 week) postoperative cognitive dysfunction (POCD) between propofol-based total intravenous anesthesia (TIVA) and volatile anesthesia with sevoflurane in adult patients undergoing elective coronary artery bypass graft surgery (CABG) with cardiopulmonary bypass (CPB).

Design: This was a prospective randomized single-blinded study.

Setting: The study was conducted at a single institution, the Sree Chitra Tirunal Institute for Medical Sciences and Technology, a tertiary care institution and university-level teaching hospital.

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Short tandem repeats (STRs) or microsatellites are short, tandemly repeated DNA sequences that involve a repetitive unit of 1-6 bp. DNA isolation and purification from a large number and often compromised samples gives problems to forensic labs for STR typing. Many of the conventional methods used in the isolation and purification of DNA from forensic samples are time consuming, expensive, hazardous for health and are often associated with greater risks of cross contamination.

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An efficient and interesting -centered umpolung method has been disclosed to construct beneficial S-N bonds, furnishing -sulfenylimines, which can readily be converted into the corresponding sulfonamide derivatives in a one-pot sequential operation. -Sulfenylimines are potent intermediates in organic synthesis, whereas sulfonamides are of major molecular interest due to their rich biological activities and wide applicability in medicinal chemistry. Owing to the simple reaction conditions and setup, this protocol displays a broad and versatile substrate scope, resulting in excellent functional group tolerability toward the synthesis of both -sulfenylimines and sulfonamides.

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Article Synopsis
  • This study aimed to assess how three different toothbrush designs affect enamel surface abrasion using extracted human teeth as samples.
  • A controlled experiment involved brushing the teeth with various toothbrushes (flat trim, zigzag, bi-level) for two weeks, measuring the surface roughness afterward.
  • Results showed that flat trim toothbrushes caused the least abrasion, while zigzag patterns led to the most damage, indicating that bristle design significantly impacts enamel safety during brushing.
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