Publications by authors named "K Umezu"
The ,-acetal derived from diethyl mesoxalate (DEMO) undergoes elimination of acetic acid upon treatment with a base, leading to the formation of -acylimine in situ. Lithium acetylide readily attacks the imino group to afford ,1,1-tricarbonylated propargylamines. When the resulting propargylamine reacts with butyllithium, ring closure occurs between the ethynyl and carbamoyl groups, yielding 2,5-disubstituted oxazole-4-carboxylates.
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- Postmortem heart specimens are crucial for studying congenital heart defects but are increasingly difficult to obtain, prompting the need for effective archiving methods.
- The study scanned 88 wax-infiltrated heart specimens using advanced imaging and 3D printing technology to create detailed digital models, forming an interactive online atlas.
- The results highlighted a variety of heart defects in the specimens, and the methods developed are valuable for preserving and sharing these important anatomical resources.
Unlabelled: Ductus venosus stenting via a transumbilical approach for pulmonary venous obstruction in infracardiac total anomalous pulmonary venous connection has been described. In a 902-gram infant who was diagnosed with asplenia syndrome and infracardiac total anomalous pulmonary venous connection, ductus venosus stenting was attempted by a transumbilical approach. However, ductus venosus stenting was discontinued due to bleeding from the portal vein.
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- * The analysis involved 17 patients, divided into two groups: biventricular repair (BVR) and univentricular repair (UVR) candidates, comparing their echocardiogram data before and after surgical interventions.
- * Results showed significant LVOT growth in BVR candidates and notable increases in both the neo-aortic valve and neo-ascending aorta measurements for UVR candidates, indicating positive outcomes from the bPAB procedure prior to arch
Motile cilia are dynamic hair-like structures covering epithelial surfaces in multiple organs. The periodic coordinated beating of cilia creates waves propagating along the surface, known as the metachronal waves, which transport fluids and mucus along the epithelium. Motile ciliopathies result from disrupted coordinated cilia beating and are associated with serious clinical complications, including reproductive disorders.
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