A new mixed-valence Cu/Cu three-dimensional coordination polymer constructed with an N,O-donor ligand generated via solvothermal synthesis: structural features and magnetic properties.

A new mixed-valence Cu/Cu three-dimensional coordination polymer, poly[[diaquabis[μ-2-(pyrazin-2-yl)quinoline-4-carboxylato]dicopper(I)copper(II)] bis(tetrafluoridoborate)], {[Cu(CHNO)(HO)](BF)}, was synthesized and characterized, with 2-(pyrazin-2-yl)quinoline-4-carboxylic acid being employed as a linker ligand. The ligand was isolated as its hydrochloride salt, 4-carboxy-2-(pyrazin-2-yl)quinolin-1-ium chloride dihydrate, CHNO·Cl·2HO. The compounds show luminescence at 550 nm for the ligand and at 565 nm for the polymer at 297 K.

A new photoluminescent coordination polymer constructed with an N-donor ligand having extended coordination capabilities derived from quinoline and pyridine.

Employment of the organic 2-(pyridin-4-yl)quinoline-4-carboxylic acid ligand with extended coordination capabilities leads to the formation of the one-dimensional copper(II) coordination polymer catena-poly[[diaquacopper(II)]-bis[μ-2-(pyridin-4-yl)quinoline-4-carboxylato]-κN:O;κO:N], {[Cu(CHNO)(HO)]·2HO}, under hydrothermal conditions. The ligand, isolated as its hydrochloride salt, namely, 4-(4-carboxyquinolin-2-yl)pyridinium chloride monohydrate, CHNO·Cl·HO, reveals a pseudosymmetry element (translation a/2) in its crystal structure. The additional pyridyl N atom, in comparison with the previously reported analogues with an arene ring instead of the pyridyl ring in the present ligand molecule, promotes the formation of a one-dimensional coordination polymer, rather than discrete molecules.

Regulation of alkaline phosphatase and alpha 2(I) procollagen synthesis during early intramembranous bone formation in the rat mandible.

We have studied intramembranous bone formation in the developing rat mandible. In this system discrete developmental stages can be readily distinguished: mesenchymal condensation, osteoid deposition, and mineralization. In mandibles of 14-day rat embryos avascular condensed mesenchymal cells can be discerned in a region lateral to Meckel's cartilage and anterior to the first molar bud.

Cloning and analysis of the 5' region of the rat bone/liver/kidney/placenta alkaline phosphatase gene. A dual-function promoter.

The rat bone/liver/kidney/placenta (BLKP) alkaline phosphatase (ALP) gene is expressed at high level in these particular tissues and at low levels in many other tissues. To study the mechanisms underlying the complex regulation of the rat BLKP ALP expression, we isolated a genomic clone, containing a 10.5-kb insert, which includes the promoter of the BLKP ALP gene with 2 kb of 5' flanking region, its first exon (84bp), and over 7 kb of the first intron.