Biosci Biotechnol Biochem
February 2025
Cinnamic acid (CA) is a widely distributed metabolite in plant species and is a precursor of many important plant molecules such as lignin and flavonoids. CA exists as both trans and cis isomers; the trans isomer is more common in nature. Previous reports have revealed that the cis isomer of CA (cis-CA) has auxin-like activity when exogenously applied.
View Article and Find Full Text PDFObjective: This study aimed to clarify the characteristics of distant metastasis in patients with N1a and N1b papillary thyroid carcinoma (PTC) and the significance of lateral lymph node metastasis as a risk factor for distant metastasis.
Methods: Of the 537 patients with N1a and N1b PTC who underwent surgical treatment at Hyogo Medical University from January 2013 to December 2020 and Shikoku Cancer Center from January 2007 to December 2018, 283 (79 men and 204 women) with lymph node metastasis were analyzed in this study. The median age was 58 (range, 19-93) years, and the median observation period was 73 (range, 1-152) months after surgery.
We present the X-ray crystal structure of a complex between a G-clamp and an internal loop motif of pre-mir-125a, selected from high affinity RNAs identified in a large-scale RNA-binding profile. This X-ray crystal structure reveals that the G-clamp interacts with three distinct guanine bases, forming robust bonds through hydrogen bonding and stacking interactions.
View Article and Find Full Text PDFPurpose: Polycystic ovary syndrome (PCOS) significantly affects women. This study investigated the association between serum anti-Müllerian hormone (AMH) levels and menstrual cycle disorders, and AMH for PCOS in a general cohort of young Japanese women.
Methods: We measured serum AMH levels in 528 healthy female students at two universities in Japan between 2014 and 2020.