A low purine diet has been recommended for patients with gout and hyperuricemia, but there are concerns about excessive carbohydrates and a lack of protein. A well-balanced diet in accordance with general dietary guidelines is widely recommended. The Mediterranean diet and the DASH (Dietary Approaches to Stop Hypertension) diet are also recommended for gout and hyperuricemia patients.
View Article and Find Full Text PDFThe azo-coupling reaction between 8-aminoquinoline and 3,5-dimethoxyphenol produces 2,6-dimethoxycyclohexa-2,5-diene-1,4-dione 1-[2-(quinolin-8-yl)hydrazone], CHNO. Crystallization from methanol and strong alkaline solutions produced nonsolvated and solvated crystals, respectively. The crystal structure analysis and H NMR spectroscopy studies revealed that the compound exists only as the hydrazone form.
View Article and Find Full Text PDFNaldemedine (Nal) is widely used as a therapeutic drug against opioid-induced constipation. However, patients in phase III trials are limited to those with good performance status (PS). Cancer patients may have inferior PS owing to progression of symptoms and adverse events from chemotherapy.
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