Background: Extracranial malignant germ cell tumors (GCTs) generally exhibit favorable outcomes with contemporary therapeutic approaches. However, the outcomes of pediatric GCTs in Vietnam remain unclear. This study aims to evaluate the clinical features, treatment modalities, and prognostic factors associated with survival outcomes in children with GCTs treated at Children's Hospital Number 2 (CH2) in Ho Chi Minh City, Vietnam.
View Article and Find Full Text PDFAims And Objectives: To evaluate the efficacy of treatment following coronectomy on mandibular third molars with inferior alveolar nerve (IAN) involvement.
Methods: A cross-sectional descriptive analysis was done on the mandibular third molars of 37 people (≥ 18 years old, 28 males, and 9 females) who needed a coronectomy and had a confirmed diagnosis of IAN in groups I, II, and III according to the classification of Q. Luo 2018, as found by CBCT.
Coinfections with (Mtb) and HIV-1 present a critical health challenge and require treatment for survival. We found that human M1 macrophages inhibit Mtb growth, while M2 macrophages, characterized by elevated Sirt2 expression, permit Mtb growth. Further, we found that HIV-1 augmented Sirt2 gene expression in MФs.
View Article and Find Full Text PDFBackground: Basal cell carcinomas (BCCs) are the most common cancers worldwide. Although most BCCs are amenable to local treatment, there are limited therapeutic options for surgically unresectable locally advanced and metastatic BCCs. Activation of the sonic hedgehog signalling pathway plays a significant role in the development of most BCCs.
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