Publications by authors named "K Trinkaus"

A captive 15-year-old male common raven () was presented for post-mortem examination. It had been previously presented to a local veterinarian due to a 3-4 weeks long history of abnormal respiratory sounds. Upon admission, the bird demonstrated severe dyspnea and a massive amount of mucous in the oropharynx.

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Article Synopsis
  • Diffusion basis spectrum imaging (DBSI) is more effective than diffusion tensor imaging (DTI) for identifying tissue damage in multiple sclerosis (MS) and assessing the risk of persistent black holes (PBHs), which indicate serious damage.
  • The study tracked relapsing MS patients with acute contrast-enhancing lesions (CELs) using monthly MRI scans to predict which lesions would turn into PBHs over the course of a year.
  • Results showed that higher radial and axial diffusivity metrics from DTI at their peak significantly correlated with the likelihood of CELs becoming PBHs, while DBSI metrics did not provide predictive value in the final analysis.
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Air quality is critical for public health. Residents rely chiefly on government agencies such as the Environmental Protection Agency (EPA) in the United States to establish standards for the measurement of harmful contaminants including ozone, sulfur dioxide, carbon monoxide, volatile organic chemicals (VOCs), and fine particulate matter at or below 2.5 μm.

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Introduction: Mantle cell lymphoma (MCL) is a moderately aggressive lymphoma subtype, generally viewed as incurable. For younger, fit patients, the standard of care remains various high-dose cytarabine-based induction regimens followed by autologous hematopoietic cell transplant and 3 years of rituximab maintenance. Despite reasonably good outcomes, with median progression-free survival in the range of 7 to 9 years, most patients eventually relapse, indicating a need to improve the safety and tolerability of remission induction strategies.

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Multipotent mesenchymal stromal cells (MSC) have emerged as therapeutic tools for a wide range of pathological conditions. Yet, the still existing deficits regarding MSC phenotype characterization and the resulting heterogeneity of MSC used in different preclinical and clinical studies hamper the translational success. In search for novel MSC characterization approaches to complement the traditional trilineage differentiation and immunophenotyping assays reliably across species and culture conditions, this study explored the applicability of lipid phenotyping for MSC characterization and discrimination.

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