Publications by authors named "K Townsend"
Medullary renal cell carcinomas are exceedingly rare and essentially uniformly and rapidly fatal. Expeditious diagnosis is crucial. Immediate treatment with a clinical trial or platinum-based chemotherapy is needed for metastatic disease given the aggressive nature of medullary renal cell carcinomas.
View Article and Find Full Text PDFThe rising diversity and concentration of contaminants have surpassed ecological thresholds, threatening marine ecosystems. The effects of pollutants on marine animals, particularly sea turtles, are receiving increased attention due to their role as indicators of human impacts. This study examined the health implications of contaminant exposure in three green turtle (Chelonia mydas) foraging sites in the southern Great Barrier Reef, Australia.
View Article and Find Full Text PDFBackground: Acquired angioedema due to C1-inhibitor deficiency (AAE-C1-INH) is very rare compared to its prototype, hereditary angioedema. An updated characterisation of the AAE-C1-INH cohort in UK is required to inform management.
Objectives: To describe the disease burden of AAE-C1-INH, long-term prophylaxis (LTP) and the clinical, immunochemical and treatment profiles of AAE-associated diseases in UK.
Article Synopsis
- The study aimed to analyze craniofacial tissue aging in a genetically diverse HET3 mouse model and determine if the hormone 17-alpha estradiol (17αE2) could enhance tissue health alongside increased longevity in male mice.
- Male HET3 mice were categorized into age groups and treated with a diet supplemented with 17αE2 to observe changes in craniofacial tissue volume and density.
- Results showed that while some aspects of tissue structure changed with age, treatment with 17αE2 positively affected cementum and dentin, suggesting it may help improve the health of aging dental tissues in male mice.