Beyond threats, we need more information about action - How individuals see themselves (or not) in complex social-ecological systems.

In the face of intersecting environmental crises such as climate change, biodiversity loss, and pollution, urgent action on all fronts is critical for a sustainable future. However, the complexity of these challenges can make it difficult for individuals to understand their role and identify meaningful actions. Little is known about how people perceive these interconnected social-ecological systems or their capacity to influence them.

Relationship Between Personality Traits and Emotional Impacts of the COVID-19 Pandemic on Canadian Emerging Adults.

We assessed whether traits from the four-factor vulnerability model for substance misuse are associated with the content of emotional descriptions given by Canadian university students of the impact of the COVID-19 pandemic on their lives. Personality traits were measured in 1185 first- and second-year undergraduates (mean age = 19.11 years; 79% female).

Sex differences in risk factors for incident sepsis hospitalisations: a prospective cohort study using the UK Biobank.

Background: Sepsis is a leading cause of death worldwide. The presence of most chronic conditions and other lifestyle-related risk factors increase sepsis risk. Whether there are sex differences in risk factors associated with sepsis hospitalisation is unknown.

Bi-allelic variants in MRPL49 cause variable clinical presentations, including sensorineural hearing loss, leukodystrophy, and ovarian insufficiency.

Combined oxidative phosphorylation deficiency (COXPD) is a rare multisystem disorder that is clinically and genetically heterogeneous. Genome sequencing identified bi-allelic MRPL49 variants in individuals from nine unrelated families with presentations ranging from Perrault syndrome (primary ovarian insufficiency and sensorineural hearing loss) to severe childhood onset of leukodystrophy, learning disability, microcephaly, and retinal dystrophy. Complexome profiling of fibroblasts from affected individuals revealed reduced levels of the small mitochondrial ribosomal subunits and a more pronounced reduction of the large mitochondrial ribosomal subunits.

Evaluation of a hydrogel platform for encapsulated multivalent Vibrio antigen delivery to enhance immune responses and disease protection against vibriosis in Asian seabass (Lates calcarifer).

This study reports the development and evaluation of a novel multivalent oral hydrogel vaccine designed to protect Asian seabass (Lates calcarifer) against vibriosis caused by multiple Vibrio species. The hydrogel formulation, composed of alginate and bentonite, was engineered to encapsulate three Vibrio pathogens (V. harveyi, V.