Publications by authors named "K Thiruvengadam"

Article Synopsis
  • A systematic review was conducted, analyzing 124 studies to assess the nutritional status of tribal populations affected by TB, ultimately including five studies that reported a high prevalence of malnutrition at 514 per 1000 people.
  • The findings highlight that undernutrition is a significant risk factor for TB in India, impacting over 50% of certain tribal populations and emphasizing the need for targeted intervention strategies.
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Background: Drug-resistant tuberculosis (DR-TB) is one of the challenging forms of TB to treat, not only in adults but also in children and adolescents. Further, there is a void in the treatment strategy exclusively for children due to various reasons, including paucity of pharmacokinetic (PK) data on anti-TB drugs across the globe. In this context, the present study aimed at assessing the PK of some of the anti-TB drugs used in DR-TB treatment regimens.

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This study investigated the medicinal potential of , a plant traditionally known for its therapeutic properties. The aim was to identify the phytocompounds in leaf extract and evaluate its antibacterial, antioxidant, and anticancer effects. Gas chromatography-mass spectrometry analysis was employed to characterize the phytochemical composition of the ethanol extract derived from leaves.

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Xpert MTB/RIF is recommended for the diagnosis of tuberculosis (TB) in children. We determined the performance of Xpert MTB/RIF in the diagnosis of pulmonary TB in children. The characteristics of children influencing Xpert MTB/RIF positivity were explored.

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Article Synopsis
  • - A study conducted in India examined the connection between the number of tuberculosis (TB) symptoms individuals experience and their likelihood of seeking healthcare, highlighting a significant gap in existing research.
  • - Out of over 130,000 participants, 7.3% reported TB symptoms, and only 28.1% of those sought medical help; more symptoms correlated with a higher likelihood of healthcare seeking.
  • - The research found that symptoms like expectoration, fatigue, and loss of appetite are key factors influencing healthcare decisions, suggesting that TB awareness efforts should focus more on a broader range of symptoms beyond just cough and fever.
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