Publications by authors named "K Tange"

Allergic diseases and ulcerative colitis (UC) share pathophysiological similarities. This study aimed to investigate the unclear association between allergic diseases and mucosal healing (MH), an important factor in the prognosis of UC. We studied 289 Japanese patients with UC.

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Article Synopsis
  • Nocturia, or frequent nighttime urination, is a common symptom in patients with lower urinary tract syndrome (LUTS), and its link to ulcerative colitis (UC) has not been widely studied.
  • A study was conducted with 287 Japanese UC patients, who were categorized based on their nighttime urination frequency and evaluated for mucosal healing (MH) and clinical remission (CR) using survey data.
  • Results indicated that higher frequencies of nighttime urination are associated with lower rates of mucosal healing, particularly in younger patients and those in clinical remission, suggesting that nocturia could be a potential indicator of disease status in UC patients.
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Background The ABO blood type has been associated with several digestive diseases. Some evidence has shown an association between ABO blood type and clinical outcomes among Asian patients with Crohn's disease. However, there are no reports about the association between ABO blood type and clinical outcomes in ulcerative colitis (UC).

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Socioeconomic status is a risk factor for poor disease prognosis. No studies of patients with ulcerative colitis (UC) have investigated the association between socioeconomic status and erectile dysfunction (ED), although UC is independently positively associated with ED. Therefore, the purpose of this survey to evaluate this issue in Japanese patients with UC.

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Double-stranded RNA-activated protein kinase R (PKR) is highly expressed in colorectal cancer (CRC). However, the role of PKR in CRC remains unclear. The aim of this study was to clarify whether C16 (a PKR inhibitor) exhibits antitumor effects and to identify its target pathway in CRC.

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