Publications by authors named "K Tamita"

Article Synopsis
  • Clinical practice guidelines recommend optimal medical therapy (OMT) for patients with stable ischemic heart disease (SIHD), focusing on lifestyle changes, medications, and exercise-based cardiac rehabilitation (CR).
  • The Pre-START study is a pilot study aimed at assessing the efficacy and safety of CR specifically for Japanese patients with SIHD who have not undergone revascularization, including 36 outpatient CR sessions within 5 months.
  • The primary goal is to measure changes in health-related quality of life and exercise capacity over 6 months, providing crucial data for future studies on CR in SIHD patients.
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The present study investigated the clinical value of myocardial contrast-delayed enhancement (DE) with multidetector computed tomography (MDCT) without iodine re-injection immediately after primary percutaneous coronary intervention (PCI) for predicting future cardiovascular events after acute myocardial infarction (AMI). We performed a prospective study in which 263 consecutive patients with first AMI successfully treated with primary PCI were enrolled. Sixty-four-slice MDCT without the re-injection of contrast medium was performed immediately after PCI.

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Article Synopsis
  • Drug-eluting stent-induced vasospastic angina (DES-VSA) is a new complication in patients undergoing percutaneous coronary intervention (PCI), prompting a study to compare the effects of beta blockers (BBs) and calcium channel blockers (CCBs) on coronary events post-stenting.
  • In a study involving 52 patients, those on CCBs had a higher rate of major cardiovascular events (MACE) over 24 months compared to those on BBs (19.2% vs 3.8%).
  • Despite equal rates of acetylcholine-induced vasospasm in both groups at the 9-month mark, the CCB group experienced notably more coronary revascularizations, indicating potential drawbacks of CCB
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Background: Coronary microvascular dysfunction and obstruction (CMVO) is a strong predictor of a poor prognosis in patients with ST-segment elevation myocardial infarction (STEMI). Although research has suggested that obstructive sleep apnea (OSA) exacerbates CMVO after primary percutaneous coronary intervention, data supporting a correlation between OSA and CMVO are limited. This study was performed to investigate whether OSA is associated with CMVO, detected as microvascular obstruction on cardiovascular magnetic resonance images, in patients with STEMI.

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Background: Secondary prevention in patients with myocardial infarction (MI) is critically important to prevent ischaemic heart failure and reduce social burden. Pioglitazone improves vascular dysfunction and prevents coronary atherosclerosis, mainly via anti-inflammatory and antiatherogenic effects by enhancing adiponectin production in addition to antihyperglycemic effects, thus suggesting that pioglitazone attenuates cardiovascular events in patients with mild (HbA1c levels < 6·5%) diabetes mellitus (DM). Therefore, we evaluated the effects of pioglitazone on cardiovascular events in patients with both previous MI and mild DM.

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