Publications by authors named "K Takekoshi"
Background: Persistent physical fatigue (PPhF) accompanying daily intensive training often results in underperformance. While salivary secretory immunoglobulin A (SIgA) has been traditionally used as an immunological marker, salivary human herpesvirus 6 and/or 7 (HHV-6/7) have recently been presented as "microbiological" markers of PPhF. This study aimed to examine the monthly variabilities of salivary HHV-6/7 levels and the difference with SIgA along the training periodization.
View Article and Find Full Text PDFIntroduction: We aimed to determine the effects of exercise on cell-free DNA (cfDNA) levels and concentration changes during the menstrual cycle in participants with regular menstrual cycles and no exercise habits.
Methods: Eleven sedentary female students with regular menstrual cycles and ovulation performed bicycle exercises at 60% VO for 30 min during the menstrual, ovulatory, and luteal phases. Blood samples were collected before (Pre), immediately after (Post 0), 30 min after (Post 30), and 60 min after (Post 60) exercise.
Article Synopsis
- - The study aimed to compare serum metabolites in individuals with sarcopenia to those without, defining sarcopenia based on specific criteria regarding muscle mass and strength.
- - Metabolomic analysis revealed that individuals with sarcopenia had higher levels of hypoxanthine, galactose, and mannose, while also showing lower levels of triethanolamine and homogentisic acid compared to the non-sarcopenic group.
- - The findings suggest that hypoxanthine could serve as a potential biomarker for sarcopenia and offer new perspectives on the underlying processes of the condition, potentially aiding in early detection.
Article Synopsis
- The study aimed to explore how common post-stroke depression is in a rehabilitation ward and its impact on recovery outcomes.
- In a cohort of 114 stroke patients, 9.6% were found to have depression, which was linked to lower functional improvement and longer hospital stays compared to non-depressed patients.
- The results suggest that those with post-stroke depression experienced slower recovery and were less likely to be discharged home, highlighting the need for further research in larger populations.
Aims: Renalase, a key mediator of cross-talk between kidneys and sympathetic nervous system, exerts protective roles in various cardiovascular/renal disease states. However, molecular mechanisms underpinning renalase gene expression remain incompletely understood. Here, we sought to identify the key molecular regulators of renalase under basal/catecholamine-excess conditions.
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