Understanding slow compression of frictional granular particles by network analysis.

We consider frictional granular packings exposed to quasi-static compression rates, with a focus on systems above the jamming transition. For frictionless packings, earlier work (S. Luding , , 2022, (9), 1868-1884) has uncovered that the system evolution/response involves smooth evolution phases, interrupted by fast transitions (events).

X-ray 3D imaging-based microunderstanding of granular mixtures: Stiffness enhancement by adding small fractions of soft particles.

This research focuses on performing ultrasound propagation measurements and micro-X-ray computed tomography (µXRCT) imaging on prestressed granular packings prepared with biphasic mixtures of monodisperse glass and rubber particles at different compositions/fractions. Ultrasound experiments employing piezoelectric transducers, mounted in an oedometric cell (complementing earlier triaxial cell experiments), are used to excite and detect longitudinal ultrasound waves through randomly prepared mixtures of monodisperse stiff/soft particles. While the fraction of the soft particles is increasing linearly from zero, the effective macroscopic stiffness of the granular packings transits nonlinearly and nonmonotonically toward the soft limit, remarkably via an interesting stiffer regime for small rubber fractions between 0.

Understanding slow compression and decompression of frictionless soft granular matter by network analysis.

We consider dense granular systems in three spatial dimensions exposed to slow compression and decompression, below, during, above and well above jamming. The evolution of granular systems under slow deformation is non-trivial and involves smooth, continuous, reversible (de)compression periods, interrupted by fast, discontinuous, irreversible transition events. These events are often, but not always, associated with rearrangements of particles and of the contact network.

Elastic waves in particulate glass-rubber mixtures.

We investigate the propagation of waves in dense static granular packings made of soft and stiff particles subjected to hydrostatic stress. Physical experiments in a triaxial cell equipped with broadband piezoelectric wave transducers have been performed at ultrasound frequencies. The time of flight is measured in order to study the combined effect of applied stress and rubber content on the elastic properties of the mixtures.

CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes.

transcripts and mutations predict relapse in AML. High-risk transcripts are associated with distinct transcriptional landscapes and upregulation of early hematopoiesis genes.