Publications by authors named "K T Saracoglu"
Refractory status epilepticus (RSE) is a condition with serious mortality and morbidity rate, resistant to benzodiazepine and second-line antiepileptic drugs. This study aimed to electrophysiologically investigate the combination of NMDA receptor antagonist ketamine and GABAergic agent propofol in an RSE model induced by lithium-pilocarpine in male Sprague-Dawley rats. Seventy-two male Sprague-Dawley rats were divided into nine groups.
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- - The study aimed to assess the effectiveness of the Integrated Pulmonary Index (IPI) in monitoring patients during EBUS-TBNA procedures under sedation, specifically looking at its impact on hypoxic events compared to traditional monitoring.
- - Conducted at Dr. Lutfi Kirdar City Hospital in Istanbul, the study involved 50 patients and measured IPI values at different stages, revealing that patients with higher IPI scores experienced fewer apnea incidents and better respiratory metrics.
- - The findings suggest that IPI monitoring enhances the detection of apnea and improves respiratory safety during procedures, but further research is needed with diverse patient groups to validate these outcomes.
Article Synopsis
- * The Infrared Fluorescent Angiography Perfusion Evaluation Device (SPY) is a noninvasive tool used to assess microcirculation and perfusion in flaps during surgery.
- * A study involving 39 patients analyzed the relationship between fluid resuscitation during head and neck free flap surgery and patient outcomes, finding that changes in SPY scores were linked to longer hospital stays and additional medical interventions.
Article Synopsis
- - The study focuses on evaluating the effectiveness of a new monitoring parameter, ORi, for detecting hypoxia in morbidly obese patients undergoing elective surgery, especially compared to the standard pulse oximetry (SpO).
- - Conducted in a tertiary hospital, the observational study included 102 patients categorized by BMI and monitored their oxygen saturation during the surgical procedure, recording various critical time points for both ORi and SpO.
- - Results showed that morbidly obese patients had a faster rate of oxygen recovery with ORi (32 seconds) compared to non-obese patients (94 seconds), indicating that ORi may provide quicker alerts for hypoxia compared to traditional SpO methods.
The primary objective of this in vitro study was to prevent the risk of toxicity associated with bupivacaine, widely used in clinical practice, by using magnesium (Mg), a readily available and cost-effective element, as an adjuvant. We hypothesized that Mg might exhibit a protective effect against cytotoxicity in a colon cell culture model under conditions of bupivacaine-induced LAST. Our secondary aim was to investigate its effect on genotoxicity, apoptosis, and iROS.
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