Publications by authors named "K T Pryor"
Article Synopsis
- The study aimed to validate and recalibrate two risk prediction scores (PRAm and intrinsic surgical risk score) for assessing 30-day in-hospital mortality in pediatric patients using a large database from multiple hospitals.
- Results showed that while both scores had good discrimination (AUROC values), they produced many false positives and underperformed compared to original validations.
- Ultimately, the intrinsic surgical risk score was more effective than PRAm, but the findings suggest that relying solely on these scores might not significantly enhance patient outcome predictions.
Background: Sternal pain after cardiac surgery results in considerable discomfort. Single-injection parasternal fascial plane blocks have been shown to reduce pain scores and opioid consumption during the first 24 h after surgery, but the efficacy of continuous infusion has not been evaluated. This retrospective cohort study examined the effect of a continuous infusion of local anaesthetic through parasternal catheters on the integrated Pain Intensity and Opioid Consumption (PIOC) score up to 72 h.
View Article and Find Full Text PDFBackground: Nirmatrelvir/ritonavir (N/R) reduces severe outcomes from coronavirus disease 2019 (COVID-19); however, rebound after treatment has been reported. We compared symptom and viral dynamics in individuals with COVID-19 who completed N/R treatment and similar untreated individuals.
Methods: We identified symptomatic participants who tested severe acute respiratory syndrome coronavirus 2-positive and were N/R eligible from a COVID-19 household transmission study.
Article Synopsis
- * Researchers will perform an individual participant data meta-analysis by reviewing multiple medical databases for trials comparing high FiO (0.60-1.00) to regular FiO (0.21-0.40) and will analyze SSI rates and mortality following surgery.
- * The analysis will use statistical models to handle data clustering and assess bias, with planned subgroup analyses, including factors like mechanical ventilation use, to enhance the understanding of outcomes.