Publications by authors named "K T Haut"

Motivation in general, and social motivation in particular are important for interpersonal functioning in individuals with schizophrenia. Still, their roles after accounting for social cognition, are not well understood. The sample consisted of 147 patients with schizophrenia.

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Importance: The lack of robust neuroanatomical markers of psychosis risk has been traditionally attributed to heterogeneity. A complementary hypothesis is that variation in neuroanatomical measures in individuals at psychosis risk may be nested within the range observed in healthy individuals.

Objective: To quantify deviations from the normative range of neuroanatomical variation in individuals at clinical high risk for psychosis (CHR-P) and evaluate their overlap with healthy variation and their association with positive symptoms, cognition, and conversion to a psychotic disorder.

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Importance: The lack of robust neuroanatomical markers of psychosis risk has been traditionally attributed to heterogeneity. A complementary hypothesis is that variation in neuroanatomical measures in the majority of individuals at psychosis risk may be nested within the range observed in healthy individuals.

Objective: To quantify deviations from the normative range of neuroanatomical variation in individuals at clinical high-risk for psychosis (CHR-P) and evaluate their overlap with healthy variation and their association with positive symptoms, cognition, and conversion to a psychotic disorder.

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Facial emotion recognition is a key component of social cognition. Impaired facial emotion recognition is tied to poor psychological wellbeing and deficient social functioning. While previous research has demonstrated the potential for social cognition training to improve overall facial emotion recognition, questions remain regarding what aspects of emotion recognition improve.

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Article Synopsis
  • Individuals at Clinical High Risk for Psychosis (CHR-P) show diverse neuroanatomical profiles, which this study aimed to quantify using MRI data from a large international dataset.
  • The ENIGMA CHR-P consortium analyzed neuroimaging from 1579 CHR-P individuals and 1243 healthy controls (HC) to compare structural measures like cortical surface area and thickness.
  • Findings highlighted greater individual-level neuroanatomical divergence in CHR-P individuals compared to HC, though no significant link was found between neuroanatomical heterogeneity and the transition to psychosis.
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