[The effect of seasons on hydrolytic and transalkylating activity of phospholipase D in the mitochondrial membranes of rat liver].

The seasonal effect on the hydrolytic and transalkylating activity of phospholipase D in the membranes of rat liver has been demonstrated. In summer the hydrolytic and transalkylating activity of the phospholipase D in rat liver mitochondria increased compared to the activity in winter. This implies that the rate of the formation of phospholipids in rat liver mitochondrial membranes is higher in summer.

[The effect of Asian cobra venom on the content of rat heart and liver mitochondrial phospholipids and the protective effect of benzonal].

Administration of a cobra venom to rats resulted in decrease of heart and liver mitochondrial cardiolipins (1.88 and 1.82 times), phosphatidylethanolamines (1.

[The correlation of liver mitochondrial respiration in mammals and reptiles at different temperatures].

In the experiments with isolated mitochondria in vitro (25 degrees C) it was shown that the respiration rate in mice was 3-5 times higher compared with agamas; in this case both animal species exhibited close body mass. At the comparison of mice and tortoises with the body mass 25-30 times exceeding the one of mice 4-10 times difference in mitochondrial respiration was found. In addition this difference was more pronounced with caprilate and pyruvate than with succinate used as substrates.

[The lipolytic enzyme activity of the mitochondrial membranes of the digestive organs in heat stress in rats].

An augmentation of catalytic activity of phospholipase A and lysophospholipase A occurred in the liver mitochondria membranes and small intestine mucosa in rats subjected to heat. The augmentation of the latter's activity was significantly lesser in overheated rats.

[The effect of lipid peroxidation on the lipid and phospholipid composition of mitochondrial membranes during thermal incubation].

Alterations in the content of lipids and phospholipids were studied in rat liver mitochondrial membranes after long-term heating at 37 degrees, pH 7.4, using FeSO4-ascorbate as inductors of lipid peroxidation. Under these conditions, activation of lipid peroxidation in mitochondrial membranes led to a marked increase in the rate of hydrolysis of phosphatidylethanolamine and lysophosphatidylethanolamine, to elevated synthesis of phosphatidylserine, sphingomyelin, phosphatidic and lysophosphatidic acids, diglycerides and cholesterol esters as well as to inhibit hydrolysis of phosphatidylcholine, cardiolipin and their lyso-derivatives.