Publications by authors named "K Swe Swe-Han"
Introduction: Antimicrobial stewardship (AMS) education and interprofessional collaboration are integral to the success of a stewardship programme. An interactive interprofessional AMS workshop, designed to encourage workplace interprofessional collaboration was piloted in a tertiary hospital.
Objectives: To obtain feedback to determine the suitability and sustainability of the AMS workshop.
Background: Urinary tract infections are common bacterial infections affecting millions worldwide. Although treatment options for urinary tract infections are well established, with ciprofloxacin long considered one of the antibiotics of choice, increasing antibiotic resistance may delay the initiation of appropriate therapy. While this increase in antimicrobial resistance has been demonstrated in multiple studies around the world, there is a dearth of information from developing countries.
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- A study in KwaZulu-Natal, South Africa revealed that rifampicin resistance in tuberculosis was often missed by the GenoType MTBDR assay but detected through phenotypic methods, leading to conflicting susceptibility results.
- Patients with resistance showed significant delays, averaging 93.7 days, in starting the correct drug-resistant therapy, highlighting issues in patient management.
- Common mutations contributing to missed resistance were identified as I491F and L452P, and there was a notable prevalence of resistance to other anti-tuberculosis drugs, indicating a growing accumulation of drug resistance.
There is a lack of data on the burden of and among human immunodeficiency virus- (HIV-) infected pregnant women in South Africa. We conducted a cross-sectional study which included 385 HIV-infected pregnant women attending antenatal clinic at the King Edward VIII Hospital in Durban, South Africa. The women provided vaginal swabs which were tested for and .
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- Antimicrobial resistance is making it harder to treat infections, which is why there's a need for rapid tests to determine how effective antibiotics will be against certain bacteria.
- This study focused on identifying genetic markers of resistance in samples from a sexually transmitted infections clinic in Durban, South Africa, using real-time PCR for quick results.
- Results showed a high agreement (≥92%) between the genetic tests and traditional culture methods for detecting resistance, suggesting that these molecular assays could be useful as a fast diagnostic tool in STI management, though further research with larger groups is needed.