Mechanistic Understanding of Onychomycosis Progression and Current Advancement in the Transungual Drug Delivery System.

Onychomycosis, a nail infection prevalent in 50 to 60% of all nail illnesses globally, caused by dermatophytes, poses significant challenges to current therapies due to their limitations in effective administration. This review explores recent advancements in novel drug delivery systems while exploring the molecular mechanisms underlying onychomycosis progression. The physicochemical properties of antifungal treatments and the intricate structure of the nail plate present challenges and can be addressed by nanotechnology-enabled solutions.

Respiratory Distress Arising from a Peripheral Osteoma: A Rare Case Report.

This case report highlights a rare occurrence of respiratory distress caused by a peripheral osteoma on the lingual mandibular surface. It underscores the importance for otolaryngologists to consider atypical bone growths in differential diagnoses of dyspnea. The case emphasises the value of CBCT in detecting and managing such uncommon maxillofacial pathologies affecting the upper airway.

Predictors of Dysplasia in Oral Submucous Fibrosis: A Retrospective Observational Study.

Introduction: Oral submucous fibrosis (OSMF) is a progressive, potentially malignant disorder often associated with areca nut and tobacco consumption. Dysplasia, a key predictor of malignant transformation, is poorly understood in terms of its association with clinical and histopathological factors. This study aimed to identify the clinical and histopathological predictors of dysplasia in OSMF to enhance diagnostic accuracy and risk stratification.

A systematic study of molecular targets of cannabidiol in Alzheimer's disease.

Background: Alzheimer's disease (AD) is a prevalent, incurable, and chronic neurodegenerative condition characterized by the accumulation of amyloid-β protein (Aβ), disrupting various bodily systems. Despite the lack of a cure, phenolic compounds like cannabidiol (CBD), a non-psychoactive component of cannabis, have emerged as potential therapeutic agents for AD.

Objective: This systematic review explores the impact of different types of cannabidiol on AD, unveiling their neuroprotective mechanisms.

Facilitating spice recognition and classification: An image dataset of Indian spices.

This data paper presents a comprehensive visual dataset of 19 distinct types of Indian spices, consisting of high-quality images meticulously curated to facilitate various research and educational applications. The dataset includes extensive imagery of the following spices: Asafoetida, Bay Leaf, Black Cardamom, Black Pepper, Caraway Seeds, Cinnamon Stick, Cloves, Coriander Seeds, Cubeb Pepper, Cumin Seeds, Dry Ginger, Dry Red Chilly, Fennel Seeds, Green Cardamom, Mace, Nutmeg, Poppy Seeds, Star Anise, and Stone Flowers. Each image in the dataset has been captured under controlled conditions to ensure consistency and clarity, making it an invaluable resource for studies in food science, agriculture, and culinary arts.