Biomechanical simulations of scoliotic spinal deformity and correction.

A new approach to surgical correction of scoliosis has been advanced by us, in the form of simulation of the surgical correction system and technique. For this purpose, we developed a finite-element model of the spinal column (SFEM), applied tractions to it and determined the model stiffness so as to watch the actual spinal geometry. Having patient-simulated this SFEM, we applied to this SFEM corrective forces and determined the optimal set of forces to gain the best correction of the spinal deformity.

Presurgical finite element simulation of scoliosis correction.

For surgical correction of scoliotic spinal deformity, internal fixation systems apply lateral and distractive corrective forces. In order to gain maximal correction, a finite--element analysis of the spinal deformity correction technique has been carried out preoperatively, after first employing the spinal deformity correction finite--element model to determine the in vivo spinal stiffness. The presurgical analysis also gives us an appreciation of how the parameters of deformity, stiffness and corrective forces jointly contribute to the value of the correction index.

Finite element analysis of two dimensional steady flow in model arterial bifurcation.

The purpose of the investigation reported in this paper is to determine theoretically the fluid dynamic field in models of common iliac arterial bifurcation and to identify the flow features which might influence the predominant occurrence of atherosclerotic lesions at such sites. This has been accomplished by numerically simulating fluid flow through 90 degrees symmetric bifurcations with branch-to-trunk area ratios of 0.8-1.

Biomechanical basis of optimal scoliosis surgical correction.

For an optimal approach to surgical correction of scoliosis, it was deemed desirable to biomechanically simulate the set of corrective forces applied by alternative internal fixation systems, so as to determine and apply the internal fixation system producing the best correction under safe levels of forces applied by the fixation systems to the spinal structures. To this end, we have developed, and presented here, (1) a spinal finite-element model relating the applied corrective forces to the corrected spinal configurations, (2) a method for determining the stiffness of the patient's spine prior to surgery, (3) computerized finite-element analysis simulation of alternative internal correction-fixation systems, so as to determine the most efficacious system, (4) instrumentations for surgically implementing the recommendations of the surgical simulation analysis and (5) comparisons of the model-simulated and surgically-obtained corrected spinal configurations. These procedures together constitute the biomechanical foundations of scoliosis surgical correction.

Intrinsic indices of the left ventricle as a blood pump in normal and infarcted left ventricles.

To assess the left ventricle as a blood pump, data are collected from contrast angiograms and analysed by computer, using two-dimensional finite element analysis, to provide instantaneous distributions of intra-LV flow and differential pressure during the diastolic and ejection phases. Characteristic indices are derived for normal and infarcted LVs, and for cases before and after administration of nitroglycerin. These indices may be used to assess the degree and nature of dysfunction in coronary artery disease.