Publications by authors named "K Steffen"
Purpose Of Review: To highlight recent research on antidepressant use and weight change and explore best clinical practices for reducing weight gain and obesity risk in individuals with depression.
Recent Findings: Research on antidepressant use and weight gain suggests that genetic and biological factors including metabolizer phenotypes and inflammation can help to predict an individual's threshold for weight change among specific agents. For individuals with increased susceptibility to metabolic complications, medications including bupropion, fluoxetine, and newer agents (e.
Article Synopsis
- The study aimed to assess factors affecting the implementation of ventilator liberation guidelines for pediatric patients and create a strategy for an international collaborative effort called VentLib4Kids.
- The survey involved 26 pediatric intensive care units (PICUs) across 18 centers, gathering 409 responses from various healthcare professionals, such as doctors, nurses, and respiratory therapists.
- Three implementation tiers were established based on consensus about various practices, showing that extubation readiness testing was well-agreed upon, while more complex practices like respiratory muscle strength testing had significant gaps in perception and agreement among respondents.
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is governed by sets of co-regulated and physically clustered genes known as biosynthetic gene clusters (BGCs). To share information about BGCs in a standardized and machine-readable way, the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard and repository was initiated in 2015.
View Article and Find Full Text PDFObjective: Renourishment and weight restoration are critical first steps in anorexia nervosa (AN) treatment. The ability of the gastrointestinal tract to harvest and utilize energy from food is essential for successful weight restoration, but the functional capacity of the intestine after prolonged caloric restriction remains unknown. In an exploratory study, we quantified the stool energy content of individuals with AN before and after renourishment.
View Article and Find Full Text PDFBackground: Anterior cruciate ligament (ACL) injury is one of the most severe injuries for athletes. It is important to identify risk factors because a better understanding of injury causation can help inform athletes about risk and increase their understanding of and motivation for injury prevention.
Purpose: To investigate the relationship between anatomic factors and risk for future noncontact ACL injuries.