Publications by authors named "K Steeves"
Poly- and perfluoroalkyl substances (PFAS) are a group of compounds with uses in industry and many consumer products. Concerns about the potential health effects of these compounds resulted in regulation by the Stockholm Convention on the use of three of the most common PFAS, including perfluorooctanoic acid (PFOA). Thousands of PFAS remain in production that are unregulated and for which their toxicity is unknown.
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- Recent studies have found microplastics in human blood and placenta, but their health effects are not fully understood.
- In experiments with pregnant mice, exposure to polystyrene microplastics led to fetal growth restriction, prompting further research on polyethylene, a common type of microplastic.
- The study showed that while polyethylene exposure did not affect fetal growth, it significantly increased blood flow in the umbilical artery, indicating potential risks to placental function and adverse pregnancy outcomes.
Article Synopsis
- The study investigates how exposure to polystyrene nanoplastics in pregnant mice affects fetal brain metabolism, particularly during gestation and lactation.
- Pregnant mice were given drinking water containing nanoplastics and researchers found significant decreases in important metabolites like GABA, creatine, and glucose in the fetal brain.
- The findings suggest that maternal nanoplastic exposure disrupts normal brain development in fetuses, highlighting potential risks for human pregnancies and the need for further research.
Maternal exposure to microplastics and nanoplastics has been shown to result in fetal growth restriction in mice. In this study, we investigated the placental and fetal hemodynamic responses to plastics exposure in mice using high-frequency ultrasound. Healthy, pregnant CD-1 dams were given either 106 ng/L of 5 μm polystyrene microplastics or 106 ng/L of 50 nm polystyrene nanoplastics in drinking water throughout gestation and were compared with controls.
View Article and Find Full Text PDFContext: Patients with acromegaly (PWA) experience balance issues, despite achieving biochemical remission, that may significantly impair their quality of life.
Objective: We sought to assess the prevalence of falls and balance self-confidence in PWA in comparison with a control group. Furthermore, we investigated the effect of joint pain and function as predictors for their balance self-confidence.