Publications by authors named "K Stanford"

As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of therapeutic interventions to support healthy aging. The Fifth Annual Midwest Aging Consortium Aging Research symposium, held from April 28-30, 2024, was hosted by The Ohio State University in Columbus, Ohio and featured presentations from investigators across the Midwestern United States. This report summarizes the research presented at the symposium, whose topics included cellular senescence and the aging brain, metabolism and metabolic interventions, nutrition, redox mechanisms and biomarkers, and stress mechanisms.

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Introduction: Despite escalating rates of sexually transmitted infections (STIs) in the United States (US), there has been progressive divestment of sexual health services leading to the reliance on emergency departments (EDs) for sexual healthcare, particularly among vulnerable populations. The Sexual Wellness Clinic (SWC), a novel care delivery model operating in collaboration with the ED, offers comprehensive sexual health services.

Objectives: This study aims to analyze the demographics, STI positivity, and HIV Pre-Exposure Prophylaxis (PrEP) uptake among patients accessing the SWC.

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Article Synopsis
  • - The study aimed to assess STI testing and treatment rates, along with pregnancy services, for sexual assault survivors in U.S. emergency departments (EDs) from 2019 to 2023.
  • - Analysis of 49,047 ED visits revealed that only about 18-34% of female patients aged 15-44 received STI tests, and roughly 40% were neither tested nor treated for gonorrhea or chlamydia.
  • - Despite low testing and treatment rates, the positivity rates for chlamydia and gonorrhea were significant, indicating a critical need for improved healthcare responses for sexual assault survivors in EDs.
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  • Enterohemorrhagic Escherichia coli (EHEC) strains, linked to red meat outbreaks, pose serious global food safety issues, especially since current detection methods often yield false positives due to non-pathogenic strains.
  • This study focused on developing and validating four new hydrolysis probe assays specifically designed to detect pathogenic E. coli serogroups O26, O103, O111, and O121, showing an impressive accuracy of 94.8% in identifying virulent strains.
  • The newly standardized assays offer reliable detection tools for food laboratories worldwide, helping to mitigate waste and financial losses from incorrect positive test results associated with harmless non-pathogenic E. coli.
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Adipose tissue is crucial for medical applications such as tissue reconstruction, cosmetic procedures, and correcting soft tissue deformities. Significant advances in the use of adipose tissue have been achieved through Coleman's studies in fat grafting, which gained widespread acceptance due to its effectiveness and safety. Despite its benefits, adipose tissue grafting faces several limitations, including high absorption rates due to insufficient support or anchorage, replacement by fibrous tissue, migration from the intended site, and loss of the initial desired morphology post-administration.

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