Publications by authors named "K Stamatiou"
: 5-phosphodiesterase inhibitors (PDE-5I) have been investigated as a treatment for urinary dysfunction for almost a decade. The general perception is that they play a significant role in managing lower urinary tract symptoms (LUTS), particularly those associated with benign prostatic hyperplasia (BPH). However, the specific biochemical processes by which PDE-5I repairs urinary function are still poorly understood and there is little instrumental evidence of significant improvement in urinary symptoms.
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- - The study explores the effectiveness of intentionally unilateral prostatic artery embolization (IU-PAE) as a less complicated alternative to traditional bilateral PAE for treating benign prostatic hyperplasia, which can be technically challenging and time-consuming.
- - IU-PAE was examined in a retrospective study where 13 patients with specific criteria underwent the procedure, showing promising results in terms of reducing radiation exposure and operation time.
- - Findings indicated that patients undergoing IU-PAE experienced significantly shorter fluoroscopy time and operational duration (up to 45.8% less) compared to those who had bilateral PAE, possibly leading to better patient outcomes.
Article Synopsis
- The study investigates the role of HSP90 as a potential diagnostic marker and therapeutic target in different types of testicular cancer, particularly focusing on embryonal carcinoma.
- Researchers analyzed HSP90 expression in 84 nonmetastatic testicular cancer patients who underwent surgery, revealing varying positivity rates across tumor types.
- The findings indicate a significant correlation between HSP90 expression in tumors and surrounding normal tissue, emphasizing its potential relevance in understanding and treating testicular cancer.
Association Between Soluble Cell Adhesion Molecules (sP-Selectin, sE-Selectin, and sICAM-1) and Antibodies Against the Antigens of Proteus mirabilis in Rheumatoid Arthritis Patients.
Cureus
July 2024
Objective The purpose of this study was to examine the association between the serum concentration of soluble cell adhesion molecules (CAMs) and antibodies against antigens of () in rheumatoid arthritis (RA) patients, taking into consideration the implication of in the etiopathogenesis of RA. Methods The serum levels of soluble P-selectin (sP-selectin), soluble E-selectin (sE-selectin), and soluble intercellular adhesion molecule-1 (sICAM-1) were determined by sandwich enzyme-linked immunosorbent assay (ELISA) in 59 RA patients and 36 healthy controls. Using the same ELISA method, the serum levels of class-specific antibodies against hemolysin (HpmB), urease C (UreC), and urease F (UreF) enzymes of were also measured.
View Article and Find Full Text PDFBenign prostatic hyperplasia is a common condition causing urinary symptoms in older men. It can sometimes lead to hematuria of prostatic origin, due to increased vascularity of the enlarged gland. If this type of hematuria is severe and refractory to conservative measures, it can be life-threatening.
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