Publications by authors named "K Stadnicka"

Article Synopsis
  • Researchers synthesized a new type of aza-BODIPY with special substituents that enhance its light-absorbing properties and allow it to maintain a long-lived excited state.
  • The compound produced strong singlet oxygen formation in tests and absorbed light in the therapeutic range (678 nm), making it potentially effective for medical applications.
  • It demonstrated excellent stability under light and heat, indicating its viability for future uses in photocatalysis and photodynamic therapy.
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Article Synopsis
  • Primordial germ cells (PGCs) are essential for creating functional gametes and passing on genetic information, making them important for genetic engineering and preservation studies.
  • The study compared the effects of different handling conditions—fresh isolation, short-term cryopreservation, and long-term in vitro culture—on the expression of specific PGC marker genes from chicken embryos.
  • Results showed that PGCs maintained similar expression levels of germ cell and pluripotency markers across different conditions, with higher expression in cryopreserved samples compared to freshly isolated ones, and no significant differences between male and female PGCs.
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Due to the intensive development of novel biopharming applications, there is a need for the in vitro verification models prior to in vivo testing. Laying hen has been already applied as an animal bioreactor to produce the therapeutical enzyme in a rare disease called lysosomal acid lipase deficiency. In this study, we aimed to verify how the proteome of the transfected oviduct epithelial cells would be affected by genetic nonviral modification with the human exogene.

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The use of probiotics, prebiotics and synbiotics in poultry diets beneficially stimulates the gut microbiome thus promoting the health and welfare of the animals. In this study, we analyzed 7 poultry probiotics ( - B1 and B4, - B3, - B2, - B5, - B6, - B7) and 12 prebiotics, differing in chemical composition and source of origin (fungi, algae, animal, etc.).

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The present study aimed to test the synbiotic PoultryStar sol delivered in ovo to evaluate its effect on hatchability, productive performance and meat quality, compared to its post-hatch administration in water. On the twelfth day of embryonic incubation, 1200 fertile eggs were divided into synbiotic groups injected with 2 mg/embryo (T1) and 3 mg/embryo (T2), a saline group injected with physiological saline and an uninjected control group (C). After hatching, 120 male chicks/group were reared and chicks from the saline group were supplemented with the synbiotic via drinking water (T3).

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