Publications by authors named "K Sritharan"
Aims: Differential attainment (DA) in post graduate medical training is a recognised challenge and refers to unexplained variation across groups when split by several protected characteristics. The Royal College of Radiology is committed to fostering diversity, inclusivity, and equality with the goal of narrowing existing gaps and improving training outcomes.
Materials And Methods: This was a mixed methods study aiming to understand the causes of DA with view to helping the RCR develop strategies to address this.
Background And Purpose: MRI-guided radiotherapy (MRIgRT) offers multiple potential advantages over CT-guidance. This study examines the potential clinical benefits of MRIgRT for men with localised prostate cancer, in the setting of moderately hypofractionated radiotherapy. We evaluate two-year toxicity outcomes, early biochemical response and patient-reported outcomes (PRO), using data obtained from a multicentre international registry study, for the first group of patients with prostate cancer who underwent treatment on a 1.
View Article and Find Full Text PDFAn endovascular approach is often considered the first line treatment option for lower limb chronic limb-threatening ischemia (CLTI), which is defined by the presence of ischemic rest pain and severe tissue loss, such as ulcers or gangrene. Although the technical success rate of endovascular revascularization is high, in specific patients with advanced infrapopliteal disease and the absence of run-off tibial vessels, the so-called 'desert foot', the chance of successful endovascular revascularization is minimal. In order to avoid primary amputation, several treatment options are currently being investigated, including gene therapy and deep venous arterialization.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated the variability in contouring the prostate bed clinical target volume (CTV) on MRI among radiation oncologists, aiming to establish baseline interobserver variability (IOV) and create international consensus guidelines.
- Sixteen oncologists analyzed three MRI scans, revealing significant differences in contouring before guidelines were developed, with notable variability in overlap, distance, and volume metrics.
- After creating consensus guidelines, IOV improved, showing a decrease in maximum volume ratio and volume coefficient of variation, alongside an increase in the Dice similarity coefficient.