Publications by authors named "K Spiropoulos"

Introduction: Pleural effusions frequently signal disseminated cancer. Diagnostic markers of pleural malignancy at presentation that would assess cancer risk and would streamline diagnostic decisions remain unidentified.

Methods: A consecutive cohort of 323 patients with pleural effusion (PE) from different etiologies were recruited between 2013 and 2017 and was retrospectively analyzed.

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Article Synopsis
  • Multiple sclerosis (MS) is a chronic condition that can lead to respiratory issues and impacts the quality of life, which this study aimed to investigate in individuals with MS who can walk independently.
  • The study involved 25 MS patients and 16 healthy controls, assessing their respiratory function through tests like spirometry and cardiopulmonary exercise testing, alongside a quality of life evaluation using the SF-36 questionnaire.
  • Results indicated that while basic lung functions were generally normal, the MS group showed reduced performance in exercise tests, with significant correlations found between exercise capacity, body mass index (BMI), fatigue levels, and quality of life scores.
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Objectives: Individuals with prior cancer diagnosis are more likely to have low muscle mass (LMM) than their cancer-free counterparts. Understanding the effects of LMM on the prognosis of cancer survivors can be clinically important. The aim of this study was to investigate whether risks for all-cause and cardiovascular disease (CVD)-specific mortality differ by status of LMM in cancer survivors and a matched cohort without cancer history.

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Objective: Osteoporosis is highly prevalent among patients with chronic obstructive pulmonary disease (COPD) and most commonly presents as a vertebral compression fracture (VCF). Our objective was to quantify the effect of osteoporosis and VCFs on the mortality and pulmonary function tests (PFTs), such as forced expiratory volume in 1 second (FEV) and forced vital capacity (FVC), of patients with COPD.

Methods: A PubMed/Medline search was conducted using the search terms "chronic obstructive pulmonary disease", "osteoporosis" and "vertebral compression fracture".

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Mental health issues such as depression and anxiety are common comorbidities of individuals suffering from chronic obstructive pulmonary disease (COPD), though they are frequently underdiagnosed and consequently undertreated. To that end we sought to identify the impact of co-morbid anxiety and depression in COPD patients and evaluate recent evidence regarding the management of such cases. A Pubmed search was conducted for relevant original articles with emphasis on the past 5 years.

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