The dynamics of persisting through distress: Development of a Momentary Distress Intolerance Scale using ecological momentary assessment.

Distress tolerance, or the ability to withstand uncomfortable states, is thought to be a transdiagnostic risk factor for psychopathology. Distress tolerance is typically measured using self-report questionnaires or behavioral tasks, both of which construe distress tolerance as a trait and downplay the potential variability in distress tolerance across time and situation. The aim of the current study was to provide a method for assessing momentary distress tolerance using ecological momentary assessment to capture both within- and between-individual information.

Overdiagnosis of COPD in hospitalized patients.

Background: The diagnosis of chronic obstructive pulmonary disease (COPD) is usually made based on history and physical exam alone. Symptoms of dyspnea, cough, and wheeze are nonspecific and attributable to a variety of diseases. Confirmatory testing to verify the airflow obstruction is available but rarely used, which may result in substantial misdiagnoses of COPD.

Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores.

There were 21 patients with rapidly progressive multiple sclerosis (MS) treated on a phase 1/2 study of intense immune suppressive therapy and autologous hematopoietic stem cell (HSC) support with no 1-year mortality. Following transplantation, one patient had a confirmed acute attack of MS. Neurologic progression defined by the expanded disability status scale (EDSS) did not increase in disability by 1.

Myelographic MR imaging of the cervical spine with a 3D true fast imaging with steady-state precession technique: initial experience.

The majority of spinal magnetic resonance (MR) imaging has been performed with spin-echo sequences and spoiled gradient-echo sequences. Advances in gradient MR imaging performance now permit imaging with coherent steady-state sequences. In this study, the authors compare a three-dimensional true fast imaging with steady-state precession sequence with a three-dimensional spoiled gradient-recalled-echo sequence for MR evaluation of the cervical spine in the transverse plane.