Publications by authors named "K Sotaniemi"

Botulin is established as first-line treatment in cervical dystonia, blepharospasm, hemifacial spasm and stroke-related spasticity of the distal parts of the upper limb. In addition, many other motor disorders and muscular hyperactivity states and neurologic symptoms and manifestations, in which temporary muscle paralysis, analgesic properties and effects on the functioning of the autonomic nervous system brought about by botulin can be utilized, have become indications for use. With proper dosage, botulin has proven to be safe even in prolonged use, the effect usually lasting for years.

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Article Synopsis
  • MAO-B inhibitors may be used to treat Parkinson's disease even before functional deficits appear.
  • For younger patients (under 75) with functional deficits, treatment typically starts with a dopamine agonist or MAO-B inhibitor; otherwise, levodopa is recommended.
  • If patients experience severe symptoms like on-off fluctuations or dyskinesias despite treatment, surgical options and duodenal levodopa infusions can be explored, along with targeted rehabilitation.
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Objectives: To evaluate the risk factors for recurrent falling and mortality in Parkinson's disease (PD) in a prospective study design.

Materials And Methods: One hundred and twenty-five PD patients were included in the study. Baseline medical data were collected, and patients were clinically tested for mobility and balance.

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Objectives: Optic neuritis (ON) is a frequent initial manifestation of multiple sclerosis (MS). Autonomic failure affecting the pupillary function is known to exist in ON patients, and patients with MS are known to have more widespread autonomic dysfunction. For example, sudomotor dysfunction is well known in MS.

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Objectives: To measure sweating in patients with multiple sclerosis (MS).

Materials And Methods: Sweating was measured by an evaporimeter after a heating stimulus in 29 MS patients and in 15 healthy control subjects.

Results: The MS patients sweated markedly less than the controls.

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