Publications by authors named "K Soetaert"

The northwestern shelf of the Black Sea has been affected by eutrophication and bottom hypoxia since the sixties. Consequently, the macrozoobenthos has suffered a well-established decline in biodiversity. However, the nature of the current benthic communities remains questionable.

View Article and Find Full Text PDF

This study explores the impact of a wind storm on sediment resuspension and marine biogeochemical dynamics. Additionally, the storm took place during an expedition researching bottom trawling, enabling the direct comparison of certain natural and fisheries-related disturbances. The storm was initiated by a decline in atmospheric pressure and a 2 h period of gale force winds, which was followed by over 40 h of elevated bottom currents.

View Article and Find Full Text PDF

Tuberculosis (TB), caused by (Mtb), remains a public health issue, particularly due to multi-drug-resistant Mtb. The bacillus is wrapped in a waxy envelope containing lipids acting as essential virulence factors, accounting for the natural antibiotic resistance of mycobacteria. Telacebec (previously known as Q203) is a promising new anti-TB agent inhibiting the cytochrome complex of a mycobacterial electron transport chain (ETC).

View Article and Find Full Text PDF

Intertidal biodiversity is being severely disrupted as a result of increased anthropogenic activity. However, our knowledge about how natural gradients, human induced disturbance and biotic interactions affect biodiversity is limited. So, we investigated how three facets of alpha diversity and community composition of benthic ciliates responded to environmental and biological gradients in the intertidal zone of Zhejiang, China.

View Article and Find Full Text PDF
Article Synopsis
  • - The effectiveness of the tuberculosis (TB) treatment ethionamide relies on its activation by specific oxidases, with the compound SMARt751 enhancing this process by interacting with a key regulatory protein, VirS.
  • - SMARt751 not only increased the effectiveness of ethionamide in lab tests and mouse studies, but also made the drug effective against resistant TB strains that have mutations affecting ethionamide activation.
  • - Safety tests showed that SMARt751 is safe for use, and predictions suggest that a low daily dose of it could significantly reduce the necessary dosage of ethionamide, lessening side effects while maintaining treatment efficacy.
View Article and Find Full Text PDF