Publications by authors named "K Skowron"
Introduction: Anorexia nervosa (AN) is a psychiatric disorder with a high mortality rate and significant prevalence in the paediatric population. Preliminary reports during the COVID-19 pandemic suggested an increased incidence of AN among children and adolescents. The objective of this study was to analyse new cases of AN before, during, and after the pandemic, with a particular focus on the physical manifestations of the disease.
View Article and Find Full Text PDFThe transcription factor NRF2 plays an important role in many biological processes and is a promising therapeutic target for many disease states. NRF2 is highly expressed in the skin and is known to play a critical role in diabetic wound healing, a serious disease process for which treatment options are limited. However, many existing NRF2 activators display off-target effects due to their electrophilic mechanism, underscoring the need for alternative approaches.
View Article and Find Full Text PDF: Nutrition plays a significant role in preventive medicine, as up to 80% of chronic diseases could be avoided by adhering to healthy dietary principles. The aim of our study was to identify dietary habits, awareness, and nutrition knowledge in a random sample of Polish healthcare students and professionals. Methods: Initially, a total screened sample consisted of 1287 respondents, yet the actual response/participation rate was 634/1287.
View Article and Find Full Text PDFArticle Synopsis
- - The study examined the use of the modified pouchitis disease activity index (mPDAI) to assess symptoms and endoscopic findings among different pouchitis phenotypes in inflammatory bowel disease (IBD).
- - A total of 103 IBD patients were analyzed, revealing that patients with normal pouches had a median mPDAI of 0, while those with cuffitis had the highest median score of 4.0, indicating more severe symptoms.
- - The findings suggested that the mPDAI may have limited effectiveness in differentiating between various inflammatory phenotypes, prompting the need for further research to identify which symptoms should be monitored.
Article Synopsis
- The study examined how chronic prenatal alcohol exposure (PAE) affects pain responses to mechanical and thermal stimuli in rats, comparing a control group and an experimental group exposed to ethanol during gestation.
- Results showed that while control rats exhibited decreased pain sensitivity over time, those with PAE had higher pain thresholds, especially for mechanical stimuli shortly after birth.
- The study suggests that differences in pain pathways and disruptions in the nervous system balance may explain these altered responses, highlighting the need for more research on the mechanisms behind pain perception in individuals exposed to alcohol before birth.