Publications by authors named "K Skalsky"

Introduction: Lung transplantation (LT) is a lifesaving procedure in patients with end stage lung failure. The prevalence of coronary artery disease (CAD) in patients with lung disease is comparably high, and coronary angiography is widely used for coronary anatomy assessment prior to LT. Detection of significant CAD usually results in revascularization to minimize post-transplant cardiovascular events.

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Article Synopsis
  • The study investigates the link between abnormal cholesterol levels and cardiovascular issues in kidney transplant recipients (KTR), focusing on Major Adverse Cardiovascular Events (MACE) and mortality rates.
  • It analyzed data from 737 KTR patients over a median follow-up of nearly eight years, finding that high LDL-C levels and a high LDL-C/HDL-C ratio significantly predicted an increased risk of MACE.
  • The researchers conclude that monitoring and improving cholesterol profiles, particularly the LDL-C/HDL-C ratio, is crucial for managing cardiovascular risk in this vulnerable population.
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We investigated the recovery pattern from acute kidney injury (AKI) following acute myocardial infarction (AMI) and its association with long-term mortality. The retrospective study included AMI patients (2002-2027), who developed AKI during hospitalization. Creatinine (Cr) measurements were collected and categorized into 24 h timeframes up to 7 days from AKI diagnosis.

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Rationale & Objective: Kidney function can be adversely affected by significant tricuspid regurgitation (TR) owing to effects on cardiac output and systemic venous congestion. However, the impact of significant TR on short- and long-term kidney function following a kidney transplant remains uncertain.

Study Design: Retrospective observational cohort.

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Article Synopsis
  • End-stage renal disease significantly increases cardiovascular risks, but kidney transplantation can help reduce these risks, even in patients with systolic heart failure.
  • A study of 604 kidney transplant patients revealed that 28% experienced a notable improvement in heart function post-transplant, with female patients showing greater recovery.
  • The findings suggest that kidney transplantation can improve left ventricular systolic function in certain patients, highlighting its potential benefits even for those with heart issues.
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