Publications by authors named "K Siripanichgon"

The emergence of multidrug-resistant enterococci (MDRE) and particularly vancomycin-resistant enterococci (VRE) is considered a serious health problem worldwide, causing the need for new antimicrobials. The aim of this study was to discover and characterize bacteriocin against clinical isolates of MDRE and VRE. Over 10,000 bacterial isolates from water, environment and clinical samples were screened.

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Article Synopsis
  • Different serogroups of Vibrio cholerae, particularly O1/O139 strains, are seldom found in their natural environments, possibly due to competition with non-O1/non-O139 strains.
  • Non-O1/non-O139 strains use a contact-dependent type VI secretion system (T6SS) to suppress the growth of the pathogenic O1 El Tor strain, as indicated by bacterial inhibition assays.
  • Proteomic analysis revealed that only certain non-O1/non-O139 strains with intact hemolysin A (HlyA) can effectively inhibit the O1 strain, highlighting the role of HlyA's ricin-like domain in this competitive interaction.
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Salmonella Enteritidis has emerged as a global concern regarding quinolone resistance and invasive potential. Although quinolone-resistant S. Enteritidis has been observed with high frequency in Thailand, information on the mechanism of resistance acquisition is limited.

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Objective: To trace the history of antimicrobial resistance in Salmonella enterica serovar Enteritidis (S. Enteritidis, SE) circulating in Thailand, we characterised clinical isolates obtained during 2004-2007.

Methods: Antimicrobial resistance profiles, multi-locus variable number tandem repeat analysis (MLVA) types and 3 representative virulence determinants (spvA, sodCI and sopE) were established from SE isolates (n = 192) collected from stool and blood of patients throughout Thailand during the period 2004-2007.

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Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae are the leading causes of hospital-associated infections, but community-acquired cases are increasingly being reported. This study determined the prevalence of ESBL-producing E. coli and K.

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