Publications by authors named "K Shinozuka"

Article Synopsis
  • Serotonergic psychedelics, like LSD and psilocybin, alter consciousness and may help treat mental health issues, but how they work is still not entirely clear.
  • The study reviews subjective experiences, neuroimaging, and molecular actions, indicating LSD leads to more intense visionary experiences compared to psilocybin and alters brain connectivity patterns.
  • Findings suggest a complex relationship between different psychedelics' effects and highlight the need for standardized research methods to better understand these substances and their therapeutic potential.*
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In East Asia, high levels of atmospheric nitrogen are deposited onto land. This could elevate the nitrate levels in coastal waters river runoff, even from areas where anthropogenic sources are minimal. It is important to identify NO sources in river water and the mechanisms involved in NO runoff.

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Article Synopsis
  • * An 87-year-old man on apixaban presented to the ER with facial trauma that led to significant bleeding and airway obstruction, prompting the need for tracheal intubation.
  • * After realizing the bleeding was life-threatening and challenging to control, andexanet alfa was administered, resulting in successful hemostasis and suggesting its potential effectiveness for managing extracranial bleeding in trauma cases.
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Several medications are commonly administered to older Japanese patients. Since some of them have not been included in previously developed scales to estimate the anticholinergic burden, we have developed a new muscarinic receptor binding-based anticholinergic burden scale. This study aimed to investigate the functional inhibitory effects of 60 medications, classified as anticholinergic burden scales 3 and 2 by the anticholinergic burden scale, on muscarinic receptor-mediated contractions in the bladder and ileum.

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The reviews in this special edition have presented a primer on the state of the literature for 7 different psychedelic compounds and their plausible roles in medicine. In a common format underscoring strengths, weakness, opportunities, and threats (SWOT), this article addresses how psychedelic compounds fit into the broader health care landscape for indicated conditions. Historically, psychiatric pathologies have been treated with small-molecule compounds that have limited effect sizes and carry a variety of adverse effect profiles.

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