Background: Pyogenic spondylitis or intervertebral discitis rarely spreads into the thoracic cavity, resulting in pyothorax. Moreover, no study has reported methicillin-resistant Staphylococcus aureus (MRSA) as a cause. Conservative and surgical treatments are reportedly effective for the above-mentioned situations; however, there have been no comprehensive reports owing to the disease's rarity.
View Article and Find Full Text PDFImmune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but they have been known to cause immune-related adverse events (irAEs) by promoting T-cell activation. Neurological irAEs are rare (1%) but have a high fatality rate (11.5%).
View Article and Find Full Text PDFVertebrate embryos are protected from bacterial infection by various maternally derived factors, yet little is known about the defence mechanisms in elasmobranchs. This study aimed to characterize the intracapsular environment of freshly laid eggs of the oviparous catshark (Scyliorhinus torazame) by investigating the microbial abundance and microbiota to understand its potential contribution to embryonic defence. The egg capsule of oviparous elasmobranchs is tightly sealed until pre-hatching, after which seawater flows into the capsule, exposing the embryos to the surrounding seawater.
View Article and Find Full Text PDFOsteonecrosis of the tibia is less common than that of the femoral condyle, with no consensus on surgical indications. In this study, a medial opening wedge high tibial osteotomy (OWHTO) was performed to treat the very extensive osteonecrosis of the tibia. This case demonstrates significant symptomatic relief and functional improvement following OWHTO for spontaneous tibial plateau osteonecrosis.
View Article and Find Full Text PDFJ Hand Surg Eur Vol
September 2024
We describe the challenge associated with obtaining an initial correct diagnosis of trapezial ridge fracture and the importance of repairing the detached ligamentous tissue after excision of the trapezial ridge fragment to obtain a favourable postoperative outcome for this rare fracture.
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