Publications by authors named "K Shimojima"

Background: Facial contouring procedures are increasingly sought to address aesthetic concerns such as submental fat accumulation and lack of jawline definition. Cryolipolysis and hyaluronic acid (HA) injection have emerged as promising modalities for lower face contouring, targeting fat reduction and jawline enhancement, respectively.

Objective: This study aims to assess the efficacy and safety of a combined treatment approach involving cryolipolysis followed by HA injection for addressing lower face contour concerns.

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Article Synopsis
  • Interstitial microdeletions in the proximal region of chromosome 6 are uncommon, but this study reports 12 patients who have developmental delays linked to such microdeletions between q12 and q22.
  • The deletions were identified using chromosomal microarray testing, and genetic analysis was performed to understand the relationship between the deletions and the patients' clinical features.
  • The gene identified as significant for developmental delay, especially in cases similar to Prader-Willi syndrome, along with other potential genes, indicates that more patient information is needed to better define this genotype-phenotype relationship.
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Objectives: It was shown that mucosal immunity via salivary IgA may be related to the improvement of seasonal allergic rhinitis (SAR) symptoms, and improvement of SAR symptoms through saliva flow increase has been reported in patients using mouthguard (MG) in dental treatment. The purpose of this study was to analyze the effect of MG use on SAR symptom improvement and to clarify the role of saliva on SAR symptom development.

Methods: We recruited patients from the Kanagawa Dental University Hospital including 38 and 8 patients with SAR and non-SAR symptoms during two seasons from March 2017 to April 2018.

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  • The study focused on understanding clinical features related to PRRT2 mutations in Japanese patients suffering from benign infantile epilepsy (BIE) and paroxysmal kinesigenic dyskinesia (PKD).
  • Out of 135 patients analyzed, mutations in the PRRT2 gene were found in 104 individuals, with a higher prevalence in familial cases compared to sporadic ones, and certain mutations were identified as more common.
  • The research concluded that 68% of patients with BIE or PKD had PRRT2 mutations, and the characteristics of the epilepsy observed were consistent with clinical diagnoses.
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The mechanical properties of Advanced Pore Morphology (APM) foam elements depend strongly upon their internal porous and external structural geometry. This paper reports on a detailed investigation of external (e.g.

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