Publications by authors named "K Shimoi"

Purple yam (Dioscorea alata L.) is a tuber widely distributed in the tropics and subtropics. We previously isolated several acylated anthocyanins from purple yam.

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  • Social stress in adult mice increased blood corticosterone levels after 2 days, disrupted liver metabolism pathways at 30 days, and raised the risk of becoming overweight at 90 days.
  • A study on male BALB/c mice revealed that younger mice (2 months old) had elevated corticosterone after 2 days of stress, but levels returned to normal afterward, while older mice (14 and 26 months) showed a decrease in liver gene expression related to stress response.
  • The findings suggest that as mice age, their liver's response to stress becomes less effective, highlighting the impact of aging on health and stress reactions.
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  • The study aimed to create a new method for assessing sperm quality by measuring mitochondrial oxygen metabolism in human sperm.
  • Using normozoospermic samples, researchers optimized parameters for an extracellular flux analyzer to track oxygen consumption rates at different storage temperatures.
  • Findings showed that while sperm motility decreased at lower temperatures (4°C) compared to 37°C, overall sperm vitality and oxygen consumption remained similar, indicating that OCR could be a reliable metric for sperm quality evaluation.
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Epidemiological studies have indicated that a disturbed circadian rhythm resulting from night-shift work is a potential risk factor for breast cancer. However, the mechanism of increased risk of breast cancer by night-shift work remains unclear, and there have been few in vivo studies conducted to definitively associate the two factors. In this study, BJMC3879Luc2 mouse breast cancer cells were transplanted into BALB/c mice.

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Omega (ω) 3 fatty acid (FA) is a polyunsaturated FA (PUFA) that can modulate some mental statuses. However, most studies have not considered the functional differences between eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). We investigated associations among happiness, a sense of fulfillment and serum ω3 PUFA levels.

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