Publications by authors named "K Shawwa"
Background: Nephrotoxin exposure may worsen kidney injury and impair kidney recovery if continued in patients with acute kidney injury (AKI).
Objectives: This study aimed to determine if tiered implementation of a clinical decision support system (CDSS) would reduce nephrotoxin use in cardiac surgery patients with AKI.
Methods: We assessed patients admitted to the cardiac surgery intensive care unit at a tertiary care center from January 2020 to December 2021, and August 2022 to September 2023.
Objective: To investigate whether the use of a specific vasopressor was associated with increased mortality or adverse outcomes in patients with acute kidney injury (AKI) receiving continuous kidney replacement therapy (CKRT).
Methods: Patients with AKI who underwent CKRT between 1/1/2012-1/1/2021 at a tertiary academic hospital were included. Cox proportional hazard model was used to assess the relationship between time-dependent vasopressor dose and in-hospital mortality.
Article Synopsis
- Intravenous fluids are crucial for managing acute kidney injury (AKI) after sepsis, but they can lead to fluid overload, prompting a need for a restrictive fluid strategy for certain patients.
- A machine learning algorithm was developed and validated to identify sepsis patients with AKI who would benefit from receiving less than 500mL of fluids within 24 hours.
- The algorithm suggested that 88.2% of patients in the validation cohort would benefit from a restrictive fluid approach, leading to higher rates of early and sustained AKI reversal and lower major adverse kidney events compared to those receiving more fluids.
Background: Current classification for acute kidney injury (AKI) in critically ill patients with sepsis relies only on its severity-measured by maximum creatinine which overlooks inherent complexities and longitudinal evaluation of this heterogenous syndrome. The role of classification of AKI based on early creatinine trajectories is unclear.
Methods: This retrospective study identified patients with Sepsis-3 who developed AKI within 48-h of intensive care unit admission using Medical Information Mart for Intensive Care-IV database.
Key Points: Patients with ESKD coming from impoverished counties are less likely to be waitlisted or transplanted. Insurance status modified the relationship between county poverty rates and waitlisting/transplant.
Background: Kidney transplantation is the optimal treatment for patients with ESKD.