Publications by authors named "K Sharpe"

Article Synopsis
  • * Fecal pellet carbon (FPC) production rates were found to be significantly higher at night, mainly due to the diel vertical migration of larger copepods into near-surface waters, affecting the overall biomass and taxonomic diversity of zooplankton.
  • * The highest FPC production occurred in fall, associated with increased diversity of larger zooplankton, while summer showed the lowest production due to predation effects, indicating that estuarine FPC export is crucial for benthic-pelagic dynamics. *
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  • * Out of 112 respondents, which included both surgeons and hand therapists, the study found significant variability in surgical decision-making and imaging practices, with most centers favoring ligament reconstruction using a bone anchor.
  • * Findings suggest that there is inconsistency in the treatment approaches for UCL ruptures and a strong interest among medical professionals for future clinical trials to standardize management practices.
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  • * The article introduces a new method called top-down drug discovery (TD), which involves searching through a large database of fungi to find genetic locations that produce molecules targeting specific human proteins, like cyclin-dependent kinases (CDKs).
  • * Researchers successfully discovered two new molecules that inhibit CDKs and improved one of them to enhance its selectivity and effectiveness, showcasing the potential of TD for developing innovative medicines.
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The manipulation of unsealed radiopharmaceuticals by healthcare workers can cause accidental personal contamination leading to occupational radiation skin dose. The UK Ionising Radiations Regulations 2017 require that potential skin doses arising from reasonably foreseeable accident scenarios are included in risk assessments. Workers must be designated as classified if these dose estimates exceed 150 mSv equivalent dose averaged over 1 cm.

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Unlabelled: The primary objective of this study was to identify associations between the prepartum teat apex microbiome and the presence of intramammary infections (IMI) in primiparous cows during the first 5 weeks after calving. We performed a case-control study using shotgun metagenomics of the teat apex and culture-based milk data collected longitudinally from 710 primiparous cows on five organic dairy farms. Cases had higher odds of having metagenomic DNA on the teat apex prior to parturition compared to controls (OR = 38.

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